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Jason J S Barton MD PhD FRCPC
Professor, Medicine (Neurology), Ophthalmology and Visual Sciences
Associations
Department of Psychology, Neuroscience Graduate Program, Brain Research Center
Other Titles
Canada Research Chair, Michael Smith Foundation for Health Research Senior Scholar
Lab Website
Human Vision and Eye Movement Laboratory
Email
jasonbarton@shaw.ca
Research Description:
The Human Vision and Eye Movement Laboratory studies higher cerebral visual and ocular motor function in people. We use three main methodologic approaches: normal human psychophysics, studies in neurologic populations, and MRI studies (fMRI and DTI), supplemented by collaborations with researchers using event-related potentials and MEG. Our study areas include two main themes:
- object recognition: we have an extensive program investigating face recognition as the best paradigm of high-level object recognition. We direct a multi-center study of acquired prosopagnosia, recruiting patients internationally for extensive fMRI, behavioural, MEG and ERP testing. We are investigating face adaptation effects and spatial frequency preferences as well. In addition to face recognition we have programs on navigational orientation and object expertise.
- saccadic programming: we explore how saccades can be used to inform us about volitional control, in the performance of antisaccades. We examine how these difficult eye movements reveal the influences of distractors on trajectory, the inter-trial contexts that change one eye movement as a function of the previous response, and how goal representations interact in space and time. These behavioural results are translated into paradigms for fMRI work and studies in schizophrenia.
Additional areas of study include the attentional processing in Balint's syndrome, scanpath generation in face and scene processing by controls, autistic subjects and patients with visual agnosia, and the neuroanatomy of motion processing in collaboration with Debbie Giaschi.
Lab Staff
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| Magnetic resonance image of a healthy subject from a functional imaging experiment, contrasting brain signal when viewing faces versus other objects: the red region is the 'Fusiform face area'. |
Recent Publications
(Full List)
Dalrymple KA, Kingstone A, Barton JJS. Seeing trees OR seeing forests in simultanagnosia: attentional capture can be local or global. Neuropsychologia 2007;45: 871-5.
Fox CJ, Barton JJS. What is adapted in face adaptation? The neural representations of expression in the human visual system. Brain Res 2007; 1127: 80-9.
Malcolm G, Barton JJS. “Sequence-agnosia” in Bálint’s syndrome: defects in visuotemporal processing after bilateral parietal damage. J Cogn Neurosci 2007: 19: 102-8.
Manoach DS, Thakkar KN, Cain MS, Polli FE, Edelman JA, Fischl B, Barton JJS. Neural activity is modulated by trial history: A functional magnetic resonance imaging study of the effects of a previous antisaccade. J Neurosci 2007; 27: 1791-8.
Barton JJS, Radcliffe N, Cherkasova MV, Edelman J. Scan patterns during the processing of facial identity in prosopagnosia. Exp Brain Res 2007; 181: 199-21.
Barton JJS, Hefter RL, Cherkasova MV, Manoach DS. Investigations of face expertise in the social developmental disorders. Neurology 2007; 69:860-70.
Greenzang C, Manoach DS, Goff D, Barton JJS. Task-switching in schizophrenia: intact active task reconfiguration and passive inhibition in an antisaccade paradigm. Exp Brain Res 2007; 181:493-502.
Moon SY, Barton JJS, Mikulski S, Polli F, Cain MS, Hämäläinen MS, Manoach DS. Where left becomes right: a magnetoencephalographic study of sensorimotor transformation for antisaccades. Neuroimage 2007; 36: 1313-23.
Manoach DS, Ketwaroo GA, Polli FE. Thakkar KN, Barton JJS, Goff DC, Fischl B, Vangel M, Tuch DS. Reduced microstructural integrity of the white matter underlying anterior cingulate cortex is associated with increased saccadic latency in schizophrenia. Neuroimage 2007; 37: 599-610.
Hefter RL, Jerskey BA, Barton JJS. The biasing of figure-ground assignment by shading cues for objects and faces in prosopagnosia. Perception in press.
Barton JJS, Hefter RL, Malcolm GL. Spatial processing in Bálint’ syndrome and prosopagnosia: a study of three patients. J NeuroOphthalmol in press.